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Influence of E. coli endotoxin on acth induced adrenal cell steroidogenesis

โœ Scribed by R. Garcia; M.D. Viloria; A.M. Municio

Book ID
116005361
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
982 KB
Volume
22
Category
Article
ISSN
0022-4731

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## Abstract Calcium is required for ACTH stimulated steroidogenesis in adrenal tumor cells in tissue culture. In the absence of calcium, the dose of ACTH required to induce half maximum steroidogenesis was increased 30 fold. In contrast to intact adrenal glands or isolated adrenal cells, high doses