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Influence of donor MHC class I antigen expression on graft survival after rat parathyroid allotransplantation

✍ Scribed by S. Timm; W. Hamelmann; C. Otto; A. Gassel; M. Etzel; K. Ulrichs; A. Thiede; W. Timmermann

Book ID
106109009
Publisher
Springer
Year
2001
Tongue
English
Weight
117 KB
Volume
386
Category
Article
ISSN
1435-2451

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Rat parathyroid allotransplantation: Inf
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## Abstract MHC antigen expression in parathyroid tissue and its influence on graft survival after allogeneic transplantation were investigated using a heterotopic rat transplantation model. MHC class I and II expression in parathyroid tissue of Lewis (LEW), Dark Agouti (DA), and Wistar‐Furth (WF)

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To decrease immunogenicity of the rat kidney, grafts were perfused with an anti-MHC class II monoclonal antibody (mAb). How effectively this procedure blocked class II-positive cells, which were mainly dendritic in appearance, was checked by immunostaining renal sections after perfusion and comparin