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Influence of dissolution rate of sparingly soluble drugs on corneal permeability in vitro

✍ Scribed by BISRAT, M; NYSTROM, C; EDMAN, P


Book ID
123584723
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
689 KB
Volume
63
Category
Article
ISSN
0378-5173

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The usefulness of penetration enhancers in promoting drug permeation across the cornea was investigated for drugs varying from hydrophilic to lipophilic. Four purported penetration enhancers [Azone (laurocapram), hexamethylenelauramide, hexamethyleneoctanamide, and decylmethylsulfoxide] were employe