𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Influence of different tripeptides on the stability of the collagen triple helix. I. Analysis of the collagen sequence and identification of typical tripeptides

✍ Scribed by R. Dölz; E. Heidemann

Book ID
102765978
Publisher
Wiley (John Wiley & Sons)
Year
1986
Tongue
English
Weight
545 KB
Volume
25
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.

✦ Synopsis

The amino acid sequence of the collagen al(1) chain (cal0 is analyzed. Deviations of random tripeptide distribution leads to the definition of clusters. Inside these regions, collagen-typical tripeptides are located. Besides Gly-Pro-Hyp, Gly-PreAla, and Gly-Ala-Hyp, the polar sequences Gly-Glu-Hyp, Gly-Ala-Arg, Gly-Glu-Arg, and Gly-Pro-Lys form typical sequences. The neighborhood of each tripeptide is analyzed and classified. The proximity to the collagen-typical tripeptides is registered. Cluster theory: Less-typical sequences also fold as members of the collagen triple helix and they are as reasonable as well as important for the collagen structure as the cluster tripeptides, but only the latter are important for the nucleation of the triplehelical folding.

📜 SIMILAR VOLUMES

Influence of different tripeptides on th
Influence of different tripeptides on the stability of the collagen triple helix. II. An experimental approach with appropriate variations of a trimer model oligotripeptide
✍ S. Thakur; D. Vadolas; H.-P. Germann; E. Heidemann 📂 Article 📅 1986 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 295 KB 👁 1 views

A collagen model peptide comprising three covalently cross-linked chains (Ala-Gly-ProIg with a stable triple-helix conformation was utilized as the constant part of elongated model peptides of different composition.

Influence of chirality, amino acid seque
Influence of chirality, amino acid sequence, and protecting groups on the intramolecular interaction behavior of dipeptide and tripeptide derivatives
✍ Monika Plass; Alfred Kolbe 📂 Article 📅 1998 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 748 KB

## Groups on the Intramolecular Interaction Behavior of Dipeptide and Tripeptide Derivatives The intramolecular interaction of protected dipeptides and tripeptides containing the amino acid units Ala, Phe, and Val was studied by means of ir spectroscopy. The NH and CO regions of the compounds diss

Ab initio molecular orbital study of the
Ab initio molecular orbital study of the amide I vibrational interactions between the peptide groups in di- and tripeptides and considerations on the conformation of the extended helix
✍ Hajime Torii; Mitsuo Tasumi 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 325 KB 👁 2 views

Interrelationships among the coupling between the amide I vibrations of peptide groups, the wavenumber A-E 1 di †erence of the amide I mode and the conformation of helical polypeptide chains were examined theoretically. Ab initio molecular orbital (MO) calculations were performed for a glycine dipep