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Influence of diagnostic and therapeutic procedures on the distribution of cervical intraepithelial neoplasia

✍ Scribed by Ralph M. Richart


Publisher
John Wiley and Sons
Year
1966
Tongue
English
Weight
764 KB
Volume
19
Category
Article
ISSN
0008-543X

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✦ Synopsis


Patients with colpomicroscopically visible lesions of dysplasia or CIS were biopsied systematically and then were followed by direct observation using colpomicroscopy and by cytology. These observations indicate that under certain circumstances a single punch biopsy may produce a n immediate cure, a delayed cure or a change in the distribution of an area of cervicaI intraepitheIia1 neoplasia (dysplasia or carcinoma in situ). These sequelae may reflect the dependence of areas of CIN o n contiguity with the squamo-columnar junction for their continued survival. T h e delayed influence of biopsy procedures on the distribution and natural history of CIN militates against their being used as part of long-term follow-up studies of the course of these lesions.


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