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Influence of CYP2D6 genotype on the disposition of the enantiomers of venlafaxine and its major metabolites in postmortem femoral blood

✍ Scribed by Maria Kingbäck; Louise Karlsson; Anna-Lena Zackrisson; Björn Carlsson; Martin Josefsson; Finn Bengtsson; Johan Ahlner; Fredrik C. Kugelberg

Book ID
113628848
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
322 KB
Volume
214
Category
Article
ISSN
0379-0738

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The effect of food on the pharmacokinetics of the antiepileptic oxcarbazepine (OXC) was investigated in healthy volunteers. Six healthy male volunteers were treated with single peroral doses of 600 mg of oxcarbazepine (Trileptal@) after overnight fasting or a fat-and protein-rich breakfast. Mean ( k