## Abstract The etiology of lung cancer in population with little or no tobacco exposure is not well understood. Individual genetic susceptibility factors have been suggested to contribute to lung cancer risk in this population. Mutations in the p53 tumor suppressor gene are implicated in the devel
✦ LIBER ✦
Influence of common XPD and XRCC1 variant alleles on p53 mutations in lung tumors
✍ Scribed by Sai-Mei Hou; Charlotta Ryk; Annamaria Kannio; Sabrina Angelini; Susann Fält; Fredrik Nyberg; Kirsti Husgafvel-Pursiainen
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 106 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.10128
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## Abstract Genetic polymorphisms affecting expression or activity of the corresponding enzymes can influence the risk of acquiring gene mutations and various cancers. We have studied 327 bladder cancer patients with regard to the functionally related polymorphisms of __GSTM1, GSTT1, GSTP1__ and __