Influence of clofibrate on hepatic transport of bilirubin and bromosulfophthalein in rats
✍ Scribed by François Jean; Armelle Foliot; Chantal Celier; Edouard Housset; Jean-Pierre Etienne
- Book ID
- 118313247
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 363 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0006-291X
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📜 SIMILAR VOLUMES
Bilirubin and other organic anions are transported in serum avidly bound to albumin from which they are extracted and transferred into the hepatocyte where they bind to cytosolic proteins. Two abundant organic anion binding proteins, ligandin and Z-protein, were previously purified from liver cytoso
Bilirubin seems to share the biliary excretion pathway with other organic anions, but not with bile acids. We studied the effects of the organic anion ioglycamide, an iodinated contrast agent, on bilirubin metabolism in Wistar rats. This compound does not undergo conjugation and is characterized by