𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Influence of chromatin molecular changes on RNA synthesis during embryonic development

✍ Scribed by Julian Chela-Flores

Publisher
Springer
Year
1992
Tongue
English
Weight
499 KB
Volume
40
Category
Article
ISSN
0001-5342

No coin nor oath required. For personal study only.

✦ Synopsis

Two aspects of the chromatin repeat length (rt) are discussed: (i) Why is r t longer for slowly dividing cells than in rapidly dividing cells?, and (ii) Why is the temporal evolution of rt a decreasing function of time (t) in mammalian cortical neurons, whereas it is an increasing function of t for granule cells around the time of birth? These questions are discussed in terms of a hypothesis which assumes a correlation between deoxyribonucleic acid (DNA) packaging, transcription, and replication.

πŸ“œ SIMILAR VOLUMES

A molecular model of chromatin organisat
A molecular model of chromatin organisation and transcription: how a multi-RNA polymerase II machine transcribes and remodels the Ξ²-globin locus during development
✍ Hua Wong; Peter J Winn; Julien Mozziconacci πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 461 KB

## Abstract We present a molecular model of eukaryotic gene transcription. For the β‐globin locus, we hypothesise that a transcription machine composed of multiple RNA polymerase II (PolII) assembles using the locus control region as a foundation. Transcription and locus remodelling can be achieved