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INFLUENCE OF CHLORPROMAZINE AND PROMETHAZINE ON VOMITING INDUCED WITH APOMORPHINE IN MAN

โœ Scribed by Isaacs, Bernard; Macarthur, J.G.

Book ID
122976850
Publisher
The Lancet
Year
1954
Tongue
English
Weight
481 KB
Volume
264
Category
Article
ISSN
0140-6736

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In mice, apomorphine (10 mg/kg s.c.) does not induce a compulsion to gnaw, but pretreatment with antihistamines, viz. pheniramine, chlorpheniramine and mepyramine, in doses ranging from 30 to 60 mg/kg i.p. caused gnawing activity. Mepyramine showed significantly less effect when compared to the othe