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Influence of bisphosphonates on endothelial cells, fibroblasts, and osteogenic cells

✍ Scribed by C. Walter; M. O. Klein; A. Pabst; B. Al-Nawas; H. Duschner; T. Ziebart

Publisher: Springer
Year: 2009
Tongue: English
Weight: 250 KB
Volume: 14
Category: Article
ISSN: 1432-6981
DOI: 10.1007/s00784-009-0266-4

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## Abstract Osteonecrosis of the jaws (ONJ) associated with the use of bisphosphonates is a newly described entity. To elucidate the mechanism leading to ONJ and to test the hypothesis that in patients with ONJ the bisphosphonates may interfere with endothelial cell proliferation, using flow cytome