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Influence of BCG vaccine strain on the immune response and protection against tuberculosis

✍ Scribed by Nicole Ritz; Willem A. Hanekom; Roy Robins-Browne; Warwick J. Britton; Nigel Curtis

Book ID
109334949
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
421 KB
Volume
32
Category
Article
ISSN
1574-6976

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## Abstract CD4^+^CD25^+^ natural T regulatory cells (Tregs) have been shown to suppress protective immune responses in several different vaccination models. Since the effect of Tregs on vaccination against tuberculosis (Tb) was unknown, we used a murine model to investigate whether natural Tregs s