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Influence of apo E polymorphism on the response to simvastatin treatment in patients with heterozygous familial hypercholesterolemia

✍ Scribed by Peter De Kniiff; Anton F.H. Stalenhoef; Marc J.T.M. Mol; Jan A. Gevers Leuven; Jan Smit; D.Willem Erkelens; Jan Schouten; Rune R. Frants; Louis M. Havekes


Book ID
118896440
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
837 KB
Volume
83
Category
Article
ISSN
0021-9150

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Short-term effects of treatment with sim
✍ K. Purvis; A. Tollefsrud; H. Rui; E. Haug; J. Norseth; L. Viksmoen; L. Ose; H. L πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 415 KB

The effects of simvastatin 40 mg per day for 14 weeks on the pituitary-testis axis of 19 men with familial hypercholesterolaemia have been examined in a single-blind study. Simvastatin significantly reduced serum low density lipoprotein (LDL) cholesterol and triglycerides by 45% and 30%, respectivel