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Influence of an extracellular acidosis on excitatory synaptic transmission and long-term potentiation in the CA1 region of rat hippocampal slices

โœ Scribed by Kuei-Sen Hsu; Ying-Ching Liang; Chiung-Chun Huang


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
313 KB
Volume
62
Category
Article
ISSN
0360-4012

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Long-term potentiation (LTP) is a long-lasting increase in synaptic strength induced by high frequency stimulation. LTP may participate in learning and memory formation. In many synaptic systems, LTP is dependent on intact function of N-methyl-D-aspartate (NMDA) receptors. NMDA receptors may be inhi