## Abstract 3T3 cells in subconfluent culture take up leucine through a transport system which has a relatively high affinity for leucine (M system). When the culture becomes confluent, the M system is turned off and leucine is transported by another system which has a low affinity for leucine (S s
Influence of amphotericin B on leucine uptake in 3T3 cells
β Scribed by M. Foresti; P. Amati
- Book ID
- 115726124
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 307 KB
- Volume
- 732
- Category
- Article
- ISSN
- 0005-2736
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π SIMILAR VOLUMES
## Abstract Addition of 5 to 250 micromolar adenosine to the culture medium resulted in a 30β80% inhibition of the rate of uptake of 2βdeoxyglucose or 3β0βmethylglucose by sparse or confluent 3T3 cells within three hours. The inhibition of deoxyglucose uptake could be reversed partially by changing
## Abstract The objective of this investigation was to determine whether the rate of glucose uptake by mouse 3T3 cells was a primary determinant of growth rate. The experimental approach was to control the rate of glucose uptake into intracellular pools by supplying this sugar at varying concentrat