Influence of Aminonucleoside on the Pyridine Nucleotide Concentration of the Rat Kidney
β Scribed by FRANZ, H. E.; FRANZ, M.
- Book ID
- 109644178
- Publisher
- Nature Publishing Group
- Year
- 1965
- Tongue
- English
- Weight
- 351 KB
- Volume
- 206
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/206947a0
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π SIMILAR VOLUMES
Hydrolysis of NAD by a nucleotide pyrophosphatase of renal membrane fractions has been reported previously. The aim of the present study was to localize this enzyme in the rat kidney. Nucleotide pyrophosphatase was assayed in glomeruli, in three parts of the proximal tubule and in four parts of the
Rats received the equivalent of 100, 250, 500, or 700 mg/kg of 14C-aspirin orally as a suspension or as a solution of a buffered, effervescent, aspirin-containing product. Animals in each dose group were sacrificed at time intervals ranging from 0.5 to 24 hr after dosing. The 14C content of whole bl