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Influence of Age on Inotropic Response to Insulin and Insulin-Like Growth Factor I in Spontaneously Hypertensive Rats: Role of Nitric Oxide

✍ Scribed by Jun Ren; James R. Sowers; Melissa Natavio; Ricardo A. Brown

Book ID
114436238
Publisher
Royal Society of Medicine Press
Year
1999
Tongue
English
Weight
347 KB
Volume
221
Category
Article
ISSN
0037-9727

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## Abstract The synthetic activity of chondrocytes in articular cartilage declines with age, possibly as a result of decreased sensitivity to anabolic growth factors such as insulin‐like growth factor‐I. The sensitivity of these cells to insulin‐like growth factor‐I is regulated, in pan, by the syn