Influence of age and short-term starvation on the ATPase activity in the developing rat brain

✍ Scribed by J. Mourek; Dr. F. Šťastný

• Publisher: John Wiley and Sons
• Year: 1978
• Tongue: English
• Weight: 453 KB
• Volume: 11
• Category: Article
• ISSN: 0012-1630
• DOI: 10.1002/dev.420110608

✦ Synopsis

Abstract

Na^+^‐K^+^‐stimulated and Mg^++^‐dependent ATPase activities were investigated in the developing cerebral cortex, subcortical structures, and medulla oblongata of rats as was the effect of 24‐hr lasting starvation and thirst on those enzyme activities. We found (a) a developmental increase of these ATPase activities in the developing rat brain with the maximum in the cerebral cortex and with the minimum in the medulla oblongata; (b) a decrease of the ratio of these enzyme activities, which was near unity in adult animals; (c) an increase of ATPase activities in the cerebral cortex and subcortical formations of young rats under starvation conditions followed by a decrease of the Mg^++^/Na^+^‐K^+^‐ATPase activity ratios in these structures; and (d) a decrease of these activities, especially in the cerebral cortex, and an increase of the activity ratios in adult animals under starvation conditions.