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Influence of Age and Caloric Restriction on Expression of Hepatic Genes for Xenobiotic and Oxygen Metabolizing Enzymes in the Mouse

✍ Scribed by Mote, P. L.; Grizzle, J. M.; Walford, R. L.; Spindler, S. R.


Book ID
125807444
Publisher
Oxford University Press
Year
1991
Tongue
English
Weight
793 KB
Volume
46
Category
Article
ISSN
0022-1422

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## Abstract In __C. elegans,__ insulin‐like hormone signal pathway plays a significant role in longevity. In particular, __daf‐16__ gene product is indispensable factor for this lifespan‐extension. This signal pathway is critical for dauer formation, which is a similar state to hibernation in mamma