Influence of adjuvant arthritis on connective-tissue metabolism
✍ Scribed by B. Exer; P. Krupp; R. Menassé; L. Riesterer
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1976
- Tongue
- English
- Weight
- 461 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1420-908X
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The metabolic alterations in the matrix of connective tissue collagen were investigated in bone and tendon of rats with adjuvant-induced arthritis. Adjuvant arthritis was induced in rats with the immunization of Freund's adjuvant containing heat-killed Mycobacterium tuberculosis. The changes in the
## Adjuvant arthritis was induced in female Fisher rats by injecting their right hind paw with 0.1 ml Freund's complete adjuvant. The development of adjuvant arthritis was inhibited by hypophysectomy and by daily treatment of intact animals with the dopaminergic agent bromocriptine. Adjuvant arthr