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Influence of adenosine receptor agonists on benzodiazepine withdrawal signs in mice

โœ Scribed by Joanna Listos; Danuta Malec; Sylwia Fidecka

Book ID
113585577
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
236 KB
Volume
523
Category
Article
ISSN
0014-2999

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The ability of NMDA antagonist MK-801 to block the expression of opioid-like withdrawal signs was examined in bile duct-ligated mice and the signs were compared with sham operated and unoperated animals. Administration of MK-801 (0/1 mg/kg), 10 min prior to naloxone challenge, significantly reduced