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Influence of a magnesium-fluoride coating of magnesium-based implants (MgCa0.8) on degradation in a rabbit model

✍ Scribed by Martina Thomann; Christian Krause; Nina Angrisani; Dirk Bormann; Thomas Hassel; Henning Windhagen; Andrea Meyer-Lindenberg

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
612 KB
Volume
9999A
Category
Article
ISSN
1549-3296

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✦ Synopsis

Abstract

MgCa0.8 cylinders (2.5 × 25 mm^2^) were coated with a magnesium‐fluoride layer and implanted in the marrow cavities of both tibiae of 10 New Zealand White rabbits. The implantation duration was 3 and 6 months. The implants were clinically well tolerated. Micro‐computed tomography revealed a new bone formation at the edges of the implants as well as an endosteal and periosteal remodeling. Using EDX‐analysis, a calcium and phosphorus rich degradation layer could be found on the implant surface. It was covered by an incomplete layer containing fluoride. The analysis by weight before implantation and after 3 and 6 months, respectively, showed a slight decrease in volume in comparison to uncoated implants. When compared with uncoated implants, the mechanical properties of the coated implants exhibited a reduction in strength after 3 months. After 6 months, the strength of the coated implants was higher than that of uncoated cylinders. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res 2010

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