Expression of p16INK4A variants in senes
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Wineeta K.C. Weebadda; Tonya J. Jackson; Athena W. Lin
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Article
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2005
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John Wiley and Sons
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English
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## Abstract Upregulation of the p16 tumor suppressor is a hallmark of senescence in human fibroblasts. In this study, we investigated potential protein modification of p16 in senescent human fibroblasts using 2D SDSโPAGE analysis. Three distinct p16 variants with isoelectric points of 5.2, 5.4, and