Regional distribution of diazepam and it
β
G. F. Placidi; G. Tognoni; G. M. Pacifici; G. B. Cassano; P. L. Morselli
π
Article
π
1976
π
Springer
π
English
β 453 KB
Repeated administration of diazepam leads to remarkable accumulation of N-desmethyldiazepam in white matter structures and in subcortical areas such as thalamus, hypothalamus, and hypophysis. Diazepam and the hydroxylated metabolites were present in lesser amounts. The distribution pattern of diazep