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Influence of a chronic treatment on the distribution of amitryptiline and metabolites in rabbit brain

✍ Scribed by G.L. Corona; R.Maffei Facing; G. Santagostino


Book ID
115770790
Publisher
Elsevier Science
Year
1971
Tongue
English
Weight
508 KB
Volume
20
Category
Article
ISSN
0006-2952

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Regional distribution of diazepam and it
✍ G. F. Placidi; G. Tognoni; G. M. Pacifici; G. B. Cassano; P. L. Morselli πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 453 KB

Repeated administration of diazepam leads to remarkable accumulation of N-desmethyldiazepam in white matter structures and in subcortical areas such as thalamus, hypothalamus, and hypophysis. Diazepam and the hydroxylated metabolites were present in lesser amounts. The distribution pattern of diazep