## Abstract The aim of this study was to compare the efficacy of high‐dose interferon (IFN)‐α‐2b with standard dose of IFN‐α‐2b in combination with ribavirin (RBV) for patients with chronic hepatitis C virus (HCV) infection, and to investigate the predictive factors associated with virological resp
Influence of [6S]-N5 -Formyltetrahydrofolic Acid on the Bioavailability of 5-Fluorouracil Combined with Interferon-α-2b.
✍ Scribed by Martin J. Czejka; Johann Schüller; Ulrike Fogl
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 146 KB
- Volume
- 325
- Category
- Article
- ISSN
- 0365-6233
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Background: Recombinant interferon-alpha (ifn) augments the cytotoxicity of both 5-fluorouracil (5-fu) and cisplatin in vitro. a phase ii study of 5-fu and ifn resulted in response rates of 25-27% in patients with metastatic esophageal carcinoma. ## Methods: A phase ii trial was initiated to d
Gamma-Interferon (IFN-y) and the antimetabolites 5fluorouracil(5-FU) and 5-fluoro-2'-deoxyuridine (FUdR) were investigated as individual agents and in combination for their in vitro antiproliferative capacity and for their effect on the expression of HLA class-I antigen, carcinoembryonic antigen (CE