Infliximab rescue therapy in ulcerative colitis, and the effect on subsequent colectomy rates
β Scribed by S. J. Halpin; P. J. Hamlin; A. C. Ford
- Book ID
- 108606100
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 50 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0269-2813
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## COMMENT This long-term follow-up study by Sandborn et al is, to our knowledge, the first prospective study to demonstrate that a medical intervention can alter the need for colectomy in moderate-to-severe ulcerative colitis, an important finding in a
Background: Cyclosporine (CsA) or infliximab (IFX) are used as rescue therapies in steroid-refractory, severe attacks of ulcerative colitis (UC). There are no data comparing the efficacy of these two alternatives. Methods: Outcome of rescue therapy was retrospectively studied in two cohorts of pati