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Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes

✍ Scribed by Pierre-André Guerne; Robert Terkeltaub; Bruce Zuraw; Martin Lotz


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
988 KB
Volume
32
Category
Article
ISSN
0004-3591

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The constitutive and lipopolysaccharide (LPS)-induced secretion of interleukin 1 (IL 1) by cultured human monocytes and macrophages has been studied. Both freshly obtained monocytes and their culture-derived macrophages were induced by LPS to secrete similar amounts of IL 1. Such induction, however,