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Inflammatory cytokines suppress NAD(P)H:quinone oxidoreductase-1 and induce oxidative stress in cholangiocarcinoma cells

โœ Scribed by Auemduan Prawan; Benjaporn Buranrat; Upa Kukongviriyapan; Banchob Sripa; Veerapol Kukongviriyapan


Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
424 KB
Volume
135
Category
Article
ISSN
1432-1335

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โœ Guangming Liu; Xin Hu; James Varani; Subhas Chakrabarty ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 272 KB

## Abstract Ca^2+^ and the cellโ€surface calcium sensing receptor (CaSR) constitute a novel and robust ligand/receptor system in regulating the proliferation and differentiation of colonic epithelial cells. Here we show that activation of CaSR by extracellular Ca^2+^ (or CaSR agonists) enhanced the