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Inflammatory cytokines regulate microRNA-155 expression in human retinal pigment epithelial cells by activating JAK/STAT pathway

✍ Scribed by R. Krishnan Kutty; Chandrasekharam N. Nagineni; William Samuel; Camasamudram Vijayasarathy; John J. Hooks; T. Michael Redmond

Book ID
116300956
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
605 KB
Volume
402
Category
Article
ISSN
0006-291X

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## Abstract Retinal pigment epithelium (RPE) and transforming growth factor‐β (TGF‐β) have been shown to be involved in various retinal diseases. We have studied the role of inflammatory cytokines on the expression and secretion of TGF‐β in human RPE cells (HRPE). Confluent cultures of HRPE derived