Inflammatory Bowel Disease: Dysfunction of Autophagy?
β Scribed by Scharl, Michael; Rogler, Gerhard
- Book ID
- 120533609
- Publisher
- S. Karger AG
- Year
- 2012
- Tongue
- English
- Weight
- 450 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0257-2753
No coin nor oath required. For personal study only.
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Inflammatory bowel diseases are common chronic inflammatory disorders. The majority are idiopathic and can be broadly divided into Crohn's disease and ulcerative colitis. Their cause is unknown, but most hypotheses focus on a primary role for T-cell dysfunction. Conversely, there is a collection of
The etiology of human inflammatory bowel diseases (IBDs) is believed to involve inappropriate host responses to the complex commensal microbial flora in the gut, although an altered commensal flora is not completely excluded. A multifunctional cellular and secreted barrier separates the microbial fl