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Inflammatory bowel disease and innate immune response genes: the challenge of complex polygenic disorders for the clinical geneticist

โœ Scribed by B Haigh


Book ID
110888174
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
99 KB
Volume
69
Category
Article
ISSN
0009-9163

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Genetics of the innate immune response i
โœ Johan Van Limbergen; Richard K. Russell; Elaine R. Nimmo; Gwo-Tzer Ho; Ian D. Ar ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 567 KB

The discovery of nucleotide-binding oligomerization domain 2/caspase recruitment domain-containing protein 15 (NOD2/CARD15) as the first susceptibility gene in Crohn's disease (CD) has shifted the focus of research into the pathogenesis of inflammatory bowel disease (IBD) firmly to the innate immune