Inflammation-induced increase in the density of neuropeptide-immunoreactive nerve endings in rat skeletal muscle

Partial sciatic nerve ligation induced m

Partial sciatic nerve ligation induced more dramatic increase of neuropeptide Y immunoreactive axonal fibers in the gracile nucleus of middle-aged rats than in young adult rats

✍ Weiya Ma; Mark A. Bisby 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 627 KB

Neuropeptide changes in primary sensory neurons caused by partial nerve injury are likely involved in the development of neuropathic pain. In this study, using immunocytochemistry, we examined neuropeptide Y (NPY) expression in lumbar dorsal root ganglion (DRG) cells of young adult (2-3 months old)