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Inflammation in the rat paw due to urate crystals

✍ Scribed by J. Damas; G. Remacle-Volon; A. Adam


Book ID
112349544
Publisher
Springer-Verlag
Year
1984
Tongue
English
Weight
359 KB
Volume
325
Category
Article
ISSN
0028-1298

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## Abstract ## Objective The mechanism by which monosodium urate monohydrate (MSU) crystals intracellularly activate the cryopyrin inflammasome is unknown. The aim of this study was to use a mouse molecular genetics–based approach to test whether the leucine‐rich repeat (LRR) domain of cryopyrin i