Although platelet-activating factor (PAF) is implicated as an important mediator in the pathogenesis of hepatic ischemia-reperfusion (IR) injury, the precise mechanism of its action has not been studied. We examined the hypothesis that PAF may influence neutrophils by promoting the production of tum
โฆ LIBER โฆ
Inflammation and platelet-activating factor production during hepatic ischemia/reperfusion
โ Scribed by Weiguo Zhou; Mark O. McCollum; Barry A. Levine; Dr. Merle S. Olson
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 616 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0270-9139
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Cells respond to external stimuli by changes in gene expression that are largely dependent on transcription factors (TFs). We studied the behavior of some TFs in rat liver during ischemia, postischemic reperfusion, and heat shock. Knowledge of the conditions at the end of ischemia is essential to un