Pachytene analysis was undertaken in a male patient heterozygous for a 14q22q Robertsonian translocation. The relatively low rate of XY autosome association led us to examine the relationships existing between the chromosomes involved in the translocation, the rate of XY-autosome association and the
Infertile spermatozoa in a human carrier of robertsonian translocation 14;22
β Scribed by Baccio Baccetti; Serena Capitani; Giulia Collodel; Mariela Estenoz; Laura Gambera; Paola Piomboni
- Book ID
- 119418993
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 142 KB
- Volume
- 78
- Category
- Article
- ISSN
- 1556-5653
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Cytogenetic analysis of 78 spermatozoa from a man heterozygous for a t(13;14) Robertsonian translocation was performed. R banding was applied for chromosomal identification. Incidence of normal and balanced complements were respectively 50% and 41.3%. Six unbalanced complements (7.7%) were observed,
A Robertsonian translocation 45,XY, t(13q;14q) was detected in the leukocyte cultures of a phenotypically normal male. Silver staining technique for nucleolus organizer regions revealed that both acrocentrics involved in the translocation had lost their nucleolus organizers.