Infection of Human Endothelial Cells with Staphylococcus aureus Induces Transcription of Genes Encoding an Innate Immunity Response

Phorbol ester-induced transcription of a

Phorbol ester-induced transcription of an immediate-early response gene by human T cells is inhibited by co-treatment with calcium ionophore

✍ Dr. Judith L. Scott; Stephanie M. Dunn; Tao Zeng; Elizabeth Baker; Grant R. Suth 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 933 KB

## Abstract Human T cells require two discrete signals to initiate their proliferation. In Jurkat T cells the first signal can be provided by the phorbol ester TPA and the second by the calcium ionophore A23187. We have isolated a cDNA from Jurkat T cells representing mRNA induced by TPA but inhibi