Infection by Epstein-Barr virus in Hodgkin's disease is not restricted to the Reed-Sternberg cells
โ Scribed by Guido Valente; Francesco Negro; Donatella Pacchioni; Giorgio Palestro
- Book ID
- 114713562
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 225 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0007-1048
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๐ SIMILAR VOLUMES
Hodgkin and Reed-Sternberg cells are considered to represent the malignant fraction in Hodgkin's disease. Several studies have shown that the Hodgkin and Reed-Sternberg cells are chromosomally abnormal, but genetic data about the morphologically normal cell population in Hodgkin's disease are very l
## Abstract Nonisotopic in situ hybridization has been used to investigate the role of EpsteinโBarr virus (EBV) in the aetiology of pediatric Hodgkin's disease. Sections from 24 cases arising in children under the age of 15 years were hybridised with digoxigeninโlabelled probes for both EBV and cyt