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Inductive effect of tobacco smoke on mouse pulmonary and hepatic cytochrome P450 isoforms

โœ Scribed by Villard, P.H.; Seree, E.; Lacarelle, B.; Therene-Fenoglio, M.C.; Attolini, L.; Bruguerole, B.; Barra, Y.; Durand, A.; Catalin, J.

Book ID
123472543
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
114 KB
Volume
74
Category
Article
ISSN
0378-4274

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## Pulmonary cytochrome P450 monooxygenases metabolize xenobiotic chemicals, including those found in environmental tobacco smoke (ETS). Exposure to ETS beginning at birth has been shown to induce the P450 CYP1A1 by seven days of life. The effects of perinatal exposure to ETS of the rat lung on the