Induction studies of Δ1-tetrahydrocannabinol metabolism by rat and rabbit lungs
✍ Scribed by Law, Francis C.P.; So, Esther M.K.
- Book ID
- 123441699
- Publisher
- Elsevier Science
- Year
- 1981
- Weight
- 402 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0306-4492
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The in vivo liver metabolism of cannabinol has been studied in the mouse and rat by combined gas chromatography and mass spectrometry. Cannabinol glucuronide was the major metabolite of cannabinol in the mouse and was accompanied by relatively large amounts of 7-hydroxycannabinol, cannabinol-7-oic a
## Abstract The metabolism of the non‐psychotropic cannabinoid (3__R__, 4__R__)Δ^1(7)^‐tetrahydrocannabinol (**1**) (=Δ ^1(7)^‐THC) was investigated in a rat liver microsomal preparation. The metabolites obtained from the incubation mixture were separated, purified and identified by ^1^H‐NMR. spect