Induction of TRAIL-mediated glioma cell death by human T cells
✍ Scribed by Jan Dörr; Sonia Waiczies; Uwe Wendling; Bibiane Seeger; Frauke Zipp
- Book ID
- 114137512
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 198 KB
- Volume
- 122
- Category
- Article
- ISSN
- 0165-5728
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Background: High grade gliomas represent very aggressive and lethal forms of human cancer, which often exhibit recurrence after surgical intervention and resistance to conventional chemotherapeutic and radiologic treatment. the clinically approved antihypertensive agent sodium nitroprusside (snp
TRAIL/Apo-2L, a novel cytokine, is a member of the tumor necrosis factor (TNF) family and serves as an extracellular signal triggering apoptosis. TRAIL/Apo-2L is capable of killing various transformed cells but not unstimulated primary T cells. In this study, five human glioma cells (U87, U118, U178