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Induction of the NAD(P)H:quinone oxidoreductase 1 by ketoconazole and itraconazole: A mechanism of cancer chemoprotection

โœ Scribed by Hesham M. Korashy; Dion R. Brocks; Ayman O.S. El-Kadi

Book ID
116334519
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
550 KB
Volume
258
Category
Article
ISSN
0304-3835

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A series of methoxystilbenes (E and Z isomers) related to resveratrol were investigated for their effects on NQO1 induction in murine hepatoma cells and growth inhibitory effects on human cancer cell lines. Both activities were enhanced in compounds with methoxy groups on rings A and B of resveratro