Induction of the lipocyte phenotype in murine hepatic stellate cells: reorganisation of the actin cytoskeleton
β Scribed by Claudia S. Mermelstein; Fatima C. Guma; Tanira G. Mello; Vitor A. Fortuna; Regina M. Guaragna; Manoel L. Costa; Radovan Borojevic
- Book ID
- 106140675
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 230 KB
- Volume
- 306
- Category
- Article
- ISSN
- 0302-766X
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## Abstract Hepatic stellate cells (HSCs) are the major site of retinol (ROH) metabolism and storage. GRX is a permanent murine myofibroblastic cell line, derived from HSCs, which can be induced to display the fatβstoring phenotype by treatment with retinoids. Little is known about hepatic or serum
## Abstract Sphingolipids play a relevant role in cellβcell interaction, communication, and migration. We studied the sphingolipid content in the murine hepatic stellate cell line GRX, which expresses the myofibroblast phenotype, and can be induced in vitro to display the fatβstoring phenotype. Lip