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Induction of the expression of HLA class I antigens on K562 by interferons and sodium butyrate

โœ Scribed by Sutherland, Judy; Mannoni, Patrice; Rosa, Frederic; Huyat, Didier; Turner, A.Robert; Fellous, Marc


Book ID
123129797
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
626 KB
Volume
12
Category
Article
ISSN
0198-8859

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Mouse embryonal carcinoma F9 cells, upon treatment with interferons (IFNs), express major histocompatibility (MHC) Class I antigens, which are otherwise not expressed in these cells. Both I F N y and IFN-aIP increase the steady-state level of Class I mRNA within 60 min of the treatment which leads t