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Induction of tamoxifen resistance in breast cancer cells by ELF electromagnetic fields

✍ Scribed by Rainer Girgert; Hartmut Schimming; Wolfgang Körner; Carsten Gründker; Volker Hanf

Book ID: 116291369
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 142 KB
Volume: 336
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2005.08.243

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## Abstract Receptor tyrosine kinase activity is essential for erbB2 (HER2/__neu__) promotion of breast carcinogenesis, metastasis and therapeutic resistance. erbB2 kinase can be activated by dimerization with another erbB receptor, most of which bind ligands. Of these, the erbB2/erbB3 heterodimer