𝔖 Bobbio Scriptorium
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Induction of systemic TNFα in Natalizumab-treated multiple sclerosis

✍ Scribed by M. Khademi; D. Stol; T. Olsson; E. Wallström


Book ID
111065383
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
146 KB
Volume
15
Category
Article
ISSN
1351-5101

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Administration of concanavalin A (Con A) is a well-established model of acute immune-mediated hepatitis. Here, we demonstrate that intravenous injection of Con A in mice induces profound thymic atrophy. Compared to liver damage, the kinetics of Con A-induced thymic atrophy is slower and more prolong