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Induction of sister-chromatid exchanges in a rat-liver cell line with chemical carcinogens

โœ Scribed by Anthony L. Meyer; Brian J. Dean

Book ID
113254068
Publisher
Elsevier Science
Year
1981
Weight
149 KB
Volume
91
Category
Article
ISSN
0165-7992

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Induction of sister chromatid exchanges
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## Abstract The frequency of sister chromatid exchange (SCE) in WIโ€38 cells was estimated by the 5โ€bromodeoxyuridine (BrdUrd)โ€dye technique after one hour's exposure to cyclophosphamide (CY), Nโ€methylโ€Nโ€ฒโ€nitroโ€Nโ€nitrosoguanidine (MNNG), 4โ€nitroquinolineโ€1โ€oxide (4NQO), and maleic hydrazide (MH) wit