Expression of mouse cytochrome P4501A1 c
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Alma C. Trinidad; Rebekah W. Wu; Larry H. Thompson; James S. Felton
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Article
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1991
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John Wiley and Sons
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English
β 849 KB
Recombinant DNA techniques have been used to develop Chinese hamster ovary cell lines for studying chemically induced genotoxicity. These cell lines express a specific cytochrome P450 isozyme responsible for the metabolism of polycyclic aromatic hydrocarbons and exhibit defined differences in DNA re