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Induction of SCEs by mono- and bifunctional psoralens in repair proficient and deficient CHO cells

✍ Scribed by D. Arnsdorff-Roubicek; A.T. Natarajan


Book ID
113252479
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
62 KB
Volume
271
Category
Article
ISSN
0165-1161

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Recombinant DNA techniques have been used to develop Chinese hamster ovary cell lines for studying chemically induced genotoxicity. These cell lines express a specific cytochrome P450 isozyme responsible for the metabolism of polycyclic aromatic hydrocarbons and exhibit defined differences in DNA re