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Induction of resistance to hexadecylphosphocholine in the highly sensitive human epidermoid tumour cell line KB

โœ Scribed by E.A.M. Fleer; D. Berkovic; U. Grunwald; W. Hiddemann


Book ID
116166634
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
794 KB
Volume
32
Category
Article
ISSN
0959-8049

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Multidrug-resistant human kb carcinoma c
โœ Timothy C. Chambers; Robert L. Raynor; J. F. Kuo ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 750 KB

In this study we show that multidrug-resistant (MDR) human KB-VI cells are highly resistant to the cytotoxicity of okadaic acid and calyculin A, 2 toxins from marine sponges that are potent inhibitors of type-I and type-2A protein phosphatases (PPl and PP2A). Cytotoxicity and colony-forming assays i