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Induction of recessive sex-linked lethal mutations in oocytes of drosophila melanogaster by the antibiotic phleomycin

โœ Scribed by Traut, H.


Publisher
Wiley (John Wiley & Sons)
Year
1983
Weight
156 KB
Volume
5
Category
Article
ISSN
0192-2521

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Nitroguanidine (NG) and its degradation product nitrosoguanidine (NSG) were evaluated for their mutagenic potential by using Drosophila melanogaster sex-linked recessive lethal (SLRL) assay. Following 72 h of feeding exposure, NG and NSG at concentrations of 4-8 pg ml-' and 15-20 mg ml-I, respective