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Induction of quinidine metabolism and plasma protein binding by phenobarbital in dogs

โœ Scribed by Ashok Rakhit; Nicholas H. G. Holford; David J. Effeney; Sidney Riegelman

Book ID
112472623
Publisher
Springer
Year
1984
Tongue
English
Weight
1009 KB
Volume
12
Category
Article
ISSN
1573-8744

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The plasma protein binding of celecoxib was determined for animals and humans using in vitro and ex vivo methods. Eight, healthy, human volunteers (three male, five female, 20-39 years) received celecoxib (600 mg) BID for 7 days, blood samples were collected and concentrations of bound and unbound c